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Complex I deficiencies of the respiratory chain account for the majority of unfavorable neuronal degeneration in PD

In addition, AS-IV significantly downregulated the expression of TGF- and mothers against decapentaplegic homolog 3 (Smad3) proteins in liver tissue, suggesting that it may ameliorate liver injury by inhibiting the TGF-/Smad signaling pathway ( 4 -induced oxidative stress and inflammation, providing new insights into the treatment of drug-induced liver injury

Research documents CNS-mediated mechanisms distinct from peripheral vascular pathways

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