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Vigorously cleanse the catheter cap on the patients IV port with an alcohol pad/scrub hub (or the agency required cleansing agent) for at least five seconds and allow it to dry

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As a further control for the conversion of NADP + to NADPH, we simultaneously detected an increase in NADPH autofluorescence after initiating the reaction

In cell-free assays, Hyp efficiently blocked the conversion of PGH 2 to PGE 2 mediated by mPGES-1 (IC 50 = 1 M), and isolated COX enzymes were not (COX-2) or hardly (COX-1) suppressed