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Even if the main folate receptors are blocked by antibodies, leucovorin can enter the central nervous system through the reduced folate carrier (RFC) , essentially bypassing the roadblock at the FR [4]

Results: Among 3821 adults who underwent LT for ALF, 2861 patients were in the weekday and 960 in the weekend admission group

Glutathione physically binds to heavy metals and neutralizes free radicals, but in the process, it becomes oxidized and depleted

1 Introduction Epithelial ovarian cancer (EOC) accounts for approximately 95% of ovarian cancer incidence, and is a leading cause of gynecologic cancer mortality worldwide ( Folate receptor alpha (FR), encoded by the FOLR1 gene, has attracted considerable interest due to its high expression in several cancer types including those of lung and breast

doi: 10.1073/pnas.1920333117