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The results showed that loss of GSTA4 significantly decreased cell proliferation and clonogenicity, whereas it increased intracellular reactive oxygen species and cell susceptibility to 5-fluorouracil (5-FU) and oxaliplatin

Mol Cell Biochem (2016) 411(1-2):8394

In all subjects, deficient activity and expression of complexes I and II and faulty lipoylation in all analysed tissues (lymphoblasts, cultured skin fibroblasts and skeletal muscle) were detected [60,61,62,63]