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Pizzimenti S, Ciamporcero E, Daga M, Pettazzoni P, Arcaro A, Cetrangolo G, et al

74 DEPDC5 contains domains with similarities to motifs found in membrane-associated proteins

Increases in Hcy levels could result from a) lowered intake or deficiencies of vitamins B6, B12 and Folic acid or b) due to mutations in the enzymes of Met/Hcy metabolism or c) high intake of Met

In addition, the following additional adverse effects may manifest if a dose larger than 5 grams is administered: Nausea Skin rashes, hives, or allergic reactions Diarrhea Liver, renal, and nerve system toxic effects

31 Nebulized hypertonic saline in concentrations of 3% or 7% hydrates mucus, increases mucociliary clearance, and may reduce inflammatory airway processes