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(2016) demonstrated that under hypoxic conditions, HGF significantly decreased the interaction between the anti-apoptotic protein Bcl-2 and the autophagy-associated protein Bcl-1

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During oxygenated or oxygen-deprived states, hypoxia-inducible factor 1 (HIF-1) promotes Th17 differentiation by directly transcriptionally activating RORt and facilitating the formation of a tertiary complex comprising RORt, p300, and HIF-1 at the IL-17 promoter region [41]

elegans , counteracted age-related strength loss and obesity in old mice, and reduced biological age in humans

Genetic modification for plant parasitic weed management has been challenging due to the lack of identified genetic loci that confer resistance in agricultural plants