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Statements Author contributions JA was responsible for collecting samples from patients and measuring their B 12 and GSH levels

The close associations of relatively abundant Stearic acid, Amiloride, and 3,4-Dimethoxyphenylethylamine with the identified OTUs, including Escherichia marmotae , Enterobacter hormaechei , Shigella boydii , Citrobacter koseri , and Subdoligranulum var iabile notably separated h-CKD groups from healthy controls

List of all such bioinformatics and AI based tools and resources specific to breast cancer research is provided in Table 4

Akindele A, Ibe I, Adeyemi O (2011) Analgesic and Antipyretic Activities of Drymaria cordata (Linn.) Willd (Caryophyllaceae) Extract

Dencker Thorbek for technical support