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In addition to inflammation, a suppression of immunity emerged as another consequence of liver injury induced by an HFD [59]

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Furthermore, ACSL4-mediated esterification of PUFAs into peroxidation-vulnerable membrane domains establishes a self-reinforcing pathway, with elevated ACSL4 expression in stroke, AD, and PD intensifying lipid oxidative damage (Zheng et al., 2024), collectively forming an iron-dependent oxidative injury axis

Among all available aesthetic treatments, glutathione injections have gained significant attention due to their skin-brightening and antioxidant properties