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Description

This causes an inflammatory response

Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma

10.1111/cas.13701 24 LiM.ChenX.WangX.WeiX.WangD.LiuX.et al (2021)

Storage: Store at controlled room temperature

Hus group reported the orally bioavailable anti-AML PROTAC 51 , capable of inducing potent and selective UPS-dependent degradation of FLT3-ITD protein (DC 50 of 7.4 nM in MV4-11 cells), with a long-lasting and dose-dependent effect in vitro and in vivo