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This suggests that the elevated glutamate concentration following BTZ administration may result from GLAST downregulation

Considering that the water molecules were trapped largely in the hydrophobic pockets, often made contacts with or were displaced by the fragments, and did not appear to play a structural role, we anticipated that their displacement with larger non-polar moieties would improve binding of newly designed inhibitors

Weve seen entire batches of experiments produce weak or no results simply because a lab fridge was malfunctioning or a technician got careless

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