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It is a chemically defined analogue of epithalamin a peptide extract from the pineal gland developed in the Russian school of peptide bioregulators

Abbreviations ALCL: Anaplastic large cell lymphoma ALK: Anaplastic lymphoma kinase ATLL: Adult T cell leukemia/lymphoma cHL: Classical Hodgkin lymphoma DCs: Dendritic cells DLBCL: Diffuse large B cell lymphoma EBV: Epstein-Barr virus EGFR: Epidermal growth factor receptor FASN: Fatty acid synthase HGF: Hepatocyte growth factor KSHV: Kaposis sarcoma-associated herpesvirus MALT: Mucosa-associated lymphoid tissue MET: Mesenchymal-epithelial transition NKTCL: Natural killer/T cell lymphoma NOD/SCID: Non-obese diabetic/severe-combined immunodeficiency NSCLC: Non-small cell lung cancer PEL: Primary effusion lymphoma PMA: Phorbol 12-myristate 13-acetate RS cells: Reed-Sternberg cells RTK: Receptor tyrosine kinase Th cell: T helper cell TKI: Tyrosine kinase inhibitor VEGFR: Vascular endothelial growth factor receptor WHO: World Health Organization References Shiota G, Rhoads DB, Wang TC, Nakamura T, Schmidt EV

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Grotzinger, J

Cancer immunotherapy: moving beyond current vaccines