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Description

GPX4, the primary reductant in biological system, is responsible for reducing lipid peroxides by using selenocysteine as a cofactor [272]

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Furthermore, curcumin acts as a natural epigenetic modulator that inhibits EZH2, an enzyme that is often overactive in POTS and responsible for silencing the norepinephrine transporter gene, thereby helping the body clear excess stress hormones

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See the research

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A stepwise addition of isopentenyl diphosphate (IPP) takes place with dimethylallyl diphosphate (DMAPP) giving rise 20-C precursor, geranylgeranyl diphosphate (GGPP)

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Genetic factors also influence treatment response, with polymorphisms in genes such as IL23R and TNFRSF1A being associated with responses to anti-TNF therapy [200]

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