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Description

Nature 439, 484489 (2006)

They represent the most accurate and insightful understanding of the situation from both a systemic and a patient perspective

AOD-9604 is a synthetic fragment of human growth hormone (amino acids 176-191 with tyrosine modification) that has been specifically engineered to target fat cells through selective receptor activation

[PubMed abstract] O'Connor DMA, Laird EJ, Carey D, O'Halloran AM, Clarke R, Kenny RA, et al

Upon binding, this receptor activation may trigger a series of intracellular events that potentially culminate in the release of stored growth hormone from somatotroph cells (GH-producing cells) in the anterior pituitary