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Quercetin counteracts iron loading through iron chelating activity, iron homeostasis gene regulation, the attenuation of the Fenton/HaberWeiss reaction and free radical scavenging, and the inhibition of protein aggregation [142]

Cells were then resuspended in 500 L of fresh HBSS, strained through a 40 M cell strainer (BD Falcon, BD Biosciences, San Jose, Calif.), and analyzed using a flow cytometer (FACSCalibur or Accuri C6, BD Biosciences), which was equipped with 488-nm laser for excitation

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Conventional medicine often relies on warfarin or heparin to mitigate thrombotic risk in IBD patients, but these drugs are prone to cause negative side effects and require clinical monitoring (Koutroubakis 2005)

Moreover, BaP triggered genome-wide epigenetic alterations by methylation, which might cause disturbances in regulation of gene expression, and thereby induced cancer