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Ofori, Emmanuel, Daryl Ramai, Sofia Nigar, Philip Xiao, Gullamulah Shahzad, and Madhavi Reddy

IL-1 is a crucial downstream effector of NLRP3 following vaccination and its production is predictive of vaccine side effect intensity [39]

Side effects at the 12 mg level roughly doubled

Cardiovascular Thrombotic Events Advise patients to be alert for the symptoms of cardiovascular thrombotic events, including chest pain, shortness of breath, weakness, or slurring of speech, and to report any of these symptoms to their health care provider immediately [see WARNINGS]