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Chronnell CMT, Ghali LR, Quinn AG, Bull JJ, McKay IA, Philpott MP, et al

Jun 2017;32(6):501-510

Targeting NOX enzymes, especially NOX4, has shown promise in experimental models, and the dual NOX1/NOX4 inhibitor GKT137831 (setanaxib) has demonstrated anti-fibrotic efficacy in Phase II trials