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Network features were calculated using STRING and the Cytoscape plugin NetworkAnalyzer and comprise number of nodes, number of edges and expected number of edges, average node degree, network diameter and radius, characteristic path length, and network density and heterogeneity

The pK a for an amino acid is an acid dissociation constant that refers to the equilibrium between the protonated and deprotonated forms of the backbone amino group, backbone carboxyl group, and any potential acid/base component of the variable group

H.NacarE.OnlenY.OzerB.et al (2011)

It remains unclear whether pharmacological stimulation of IGF-1/PI3K/Akt signaling attenuates immobilization- or unloading-induced muscle atrophy

American Journal of Physiology-Heart and Circulatory Physiology, 303(6), H703H711