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Tobacco ( Nicotiana tabacum var

By modulating GSH levels, CHAC1 may help cancer cells manage oxidative stress, allowing them to survive under conditions that would typically induce cell death

By contrast, the upregulation of ACSL4, ALOX15, and NCOA4 promotes lipid peroxidation and intracellular iron accumulation, exacerbating cell death (42-45)