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Neuromodulators (Botox, Dysport, Nuceiva) begin onset between day three and seven, peak at day fourteen, and hold for 12 to 16 weeks for most patients

Nat Clin Pract Oncol 3 : 2440 Pegram MCD et al

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Both medications enhanced insulin secretion and reduced appetite, but tirzepatides dual action on GIP and GLP-1 pathways provides broader metabolic benefits including improved lipid profiles, blood pressure, and biomarkers of insulin sensitivity