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The Liver as the Primary Site of Ethanol Oxidation Alcohol enters the bloodstream through gastrointestinal absorption and travels through the portal vein directly to the liver

There was no significant difference in terms of age ( P = 0.58), sex ( P = 1), systolic ( P = 0.4) or diastolic ( P = 0.88) blood pressure, marital status ( P = 0.69), smoking status ( P = 0.61), or comorbidity status ( P = 1) between the L-carnitine group and the placebo group

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In addition, it has also been reported that CLOCK is available to bind to other target proteins such as the p65 subunit of NF-kB (40) which in the lens has been shown to be associated with oxidative-induced damage in human lens epithelial cells (41)