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BMC Plant Biol 10(1):130

In addition, the British National Formulary offers the following advice: Important: When prescribing an antipsychotic for administration on an emergency basis, the intramuscular dose should be lower than the corresponding oral dose (owing to absence of first-pass effect), particularly if the patient is very active (increased blood flow to muscle considerably increases the rate of absorption)

High cortisol increases sex hormonebinding globulin (SHBG), which lowers free testosterone and estradiol available to tissues

If weight loss is your primary goal, the higher protocols are recommended

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