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reported that methionine supplementation enhances T cell response in a small cohort of colorectal cancer patients oral supplement at 1000 mg/day for two weeks significantly improved CD8+ T cell cytokine production and reduced T cell apoptosis, highlighting the potential for clinical translation ( Manipulating GCN2 to enhance T cell anti-tumor immunity GCN2 plays a crucial role in regulating T cell immunity, particularly in amino acid-limited conditions and indoleamine 2,3-dioxygenase (IDO)-mediated immune suppression (105, 109, 110, 112)

In recent years, it has been demonstrated that the progression of fatty liver disease is closely associated with the risk of cardiovascular diseases

Control of regulatory T-cell differentiation and function by T-cell receptor signalling and Foxp3 transcription factor complexes

Lipid peroxidation at the membrane can disrupt the ion balance and increase membrane permeabilization [12]