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SARS-CoV-2 infection was observed to cause pathological changes including acute respiratory distress syndrome, elevated pro-inflammatory mediator release, dysregulated iron metabolism, and iron overload, with Epi administration significantly improving cardiac status in these patients (51)

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doi: 10.1016/j.immuni.2016.11.007

Autophagy regulates insulin resistance following endoplasmic reticulum stress in diabetes