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Peter de Keizer) from the Netherlands found that a drug that they developed to kill senescent cells causes dramatic improvements in mice health and essentially reverses their aging

In line with the effect of LD on the collagen fibers, this group, later on, discovered that the MMP-2 protein expression was significantly reduced in rats treated with LD with an increased tissue inhibitor of metalloproteinase-2 (TIMP-2) expression, suggesting the influence of LD on the ECM (Wang et al., 2016)

The map of TTLL6 obtained by focused classification has accession EMD-41022

Pathophysiology of systemic sclerosis: current understanding and new insights

Calomme et al