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It interferes with neurotransmitter synthesis (e.g., dopamine, serotonin), disrupts synaptic signaling, and can lead to neurodevelopmental delays, mood disorders, or cognitive decline

Hou L, Zhang J, Liu Y, Fang H, Liao L, Wang Z, et al

doi: 10.1002/hep.32449 177 OlieroMHajjarRCuisiniereTFragosoGCalveASantosMM

Figure 6: a ) Detection of autophagosome formation labeled with Premo autophagy sensor in resistant U87-R and non-resistant U87 cells after treatment with etoposide (EP) and temozolomide (TMZ) at IC 50 doses, b) Western blot figures with relative intensity of LC3-II protein (relative intensity normalized with -actin)