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Cytokine levels (IL-1, TNF-, IL-6) and LPS were measured by ELISA

Key potential benefits include: Bone density protection, helping counteract oestrogen-related bone loss Calcium metabolism regulation, reducing the likelihood of arterial calcification Skin and collagen support, especially post-40 years of age Immune balance, which may fluctuate with hormone changes The benefits of vitamin D3 and K2 for women may also extend to improved mood, fatigue management, and better absorption of other micronutrients such as magnesium and iron

Given the further application of PROTACs for clinical use, a precise understanding of the regulatory mechanisms for targeted protein degradation is needed

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