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mHTT Accumulation and Astrocyte Activation Recent literature also suggests mHTT is expressed and aggregates in astrocytes, and contributes to neuronal excitotoxicity via downregulation of glutamate transporters EAAT2/GLT1, resulting in impaired glutamate uptake (Arzberger et al., 2001

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[DOI] [PubMed] [Google Scholar] 210.Gopalakrishnan S, Hallett MA, Atkinson SJ, Marrs JA

Acknowledgments We wish to thank Daolin Mou and Yulin Chen for helping the animal experiments

Agric Food e-Newsletter 1(8):339347 Mao X, Wan Y, Yan A, Shen M, Wei Y (2012) Simultaneous determination of organophosphorus, organochlorine, pyrethriod and carbamate pesticides in Radix astragali by microwave-assisted extraction/dispersive-solid phase extraction coupled with GCMS