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Scaling, biological fouling, or fill media degradation can erode thermal performance and increase energy consumption

Parents believe that most CAM-associated treatments are either helpful or without effect but not harmful [35]

CV: Regular rate and rhythm

Finally, a 40 session trial of hyperbaric oxygen therapy showed that it has no effect on plasma GSH:GSSG in children with autistic disorder [49] and, as discussed above, incomplete data and selective reporting make it hard to interpret the findings of a randomised trial of topical glutathione before chelation [65]

4.2 Lack of specific biomarkers and translational limitations of therapeutics The clinical translation of ferroptosis-targeted strategies is bottlenecked by two critical barriers: the absence of specific, standardized biomarkers for ferroptosis in renal tissues and biofluids, and the suboptimal pharmacokinetic and safety profiles of current ferroptosis modulators