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For example, a study showed that long-term smoking was an independent factor for IPF development and that IPF patients who were smokers exhibited lower overall cellularity but higher and more severe alveolar space cellularity

10.1016/j.molcel.2018.01.024 184 MirzaeiH.GhorbaniS.KhanizadehS.NamdariH.FaghihlooE.AkbariA

The model residuals were examined visually to assess the assumptions of the model

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In addition, KD enhances translocation of nuclear factor erythroid 2-related factor 2 (Nrf2) and increases expression of glutathione peroxidase and heme-oxygenase-1 in an AD mouse model, suggesting activation of Nrf2-dependent antioxidant responses in this experimental context