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(2011) 128:94855.e941-943

Mechanistically, glutamine enhances the ability of cDC1s to deliver antigens by inducing the FLCN-FNIP2 complex to assemble and suppressing the TFEB transcription factor's activity (Fig

Some studies suggest that DHODH activity is particularly crucial under conditions of GSH depletion, while others propose that the pathway's significance varies according to tissue type and metabolic state (80, 81)