catalase superoxide dismutase glutathione peroxidase and renal concentration or activity of (SOD), Therapeutic Applications and Mechanisms of

On the contrary, the increased melanin synthesis and accumulation of these pigments occur in many types of skin disorders, including Acanthosis nigricans, Cervical Poikiloderma, melasma, Periorbital hyperpigmentation, Lentigines, neuro-degeneration associated with Parkinsons disease and skin cancer risk 6466

Kirschstein National Research Service Award T32 GM007185 to D.A.V

Although NNT is not the only mitochondrial source of NADPH, it is a major component (Ronchi et al., 2016)

Reduces Hyperpigmentation & Dark Spots Sun exposure increases melanin production , leading to dark spots, freckles, and an uneven skin tone

These effects may be helpful for muscles, tendons, ligaments, joints, and digestive tissue, especially for individuals working toward an active lifestyle, weight loss goals, or improved recovery after physical stress