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Since patient compliance was low with the previous OspA vaccine LYMErix, even outside of the fears related to autoimmunity, why was the decision made to continue with a 3-shot, plus annual boosters regimen

Reconstitute with bacteriostatic water for subcutaneous research administration

Mechanistically, androgen binds to an atypical androgen-response element within the DUSP2 promoter, promoting DUSP2 transcription and subsequently inhibiting Th2 differentiation [50]