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Look for supplements that have been third-party tested for purity and potency, and consider consulting with a healthcare provider before beginning any new supplementation regimen

Additionally, the role of non-classical ferroptosis suppressors (e.g., FSP1, DHODH, and GCH1/BH4) in ADPKD is entirely unexploredwhether these pathways compensate for GPX4 downregulation in cystic kidneys or if their dysfunction exacerbates ferroptosis susceptibility remains unknown, limiting the development of multi-targeted interventions

J Trace Elem Med Biol 62:126653

Lithium stimulates neurotrophic cell cascades, which are responsible for mediating neuron differentiation and survival, as well as synaptic modulation and plasticity