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On the other hand, majority of IGF-I actions are mediated through the union of IGF-I to its putative receptor, IGF-IR, a tyrosine kinase that is one of the most potent natural activators of Akt pathway, involving among others: mTOR, MAPK, GSK3, FOXO, HDM2, Grb2 and Shc systems, all of them closely related with cell survival, growth and proliferation[1517]

Our experience suggests that the deceased donor pool could be further expanded using EC donors without increasing complications

FLIP-G sensor could overcome the delivery and toxicity problems of chemical dye-based probes for GSH, and can also be used for real-time cytosolic monitoring of GSH, non-invasively

Plants that are engineered to grow in controlled environments, such as in plant factories, could benefit from reduced acclimation requirements, thus allowing the plants to maintain photosynthetic efficiency at optimum levels without the need for frequent adjustments