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Children: As directed by a healthcare professional

Reduced secretion of gastric acid and pepsin, from the use of H 2 blocker or proton-pump inhibitor (PPI) drugs, can reduce the absorption of protein-bound (dietary) vitamin B 12 , although not of supplemental vitamin B 12

Some researchers have studied vitamin B12 to find out if it can increase energy and endurance during exercise, but the results are inconclusive

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Long-term human safety data remains limited due to the compounds regulatory status