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Description

Results: The total sample of this study consists of 402 patients, mean age was 59.8 years, 49% female

Male Sprague-Dawley rats were fed either a control diet or a diet high in cocoa before receiving an injection of complete Freund's adjuvant (CFA) into the capsule of the temporomandibular joint

FEBS Lett 1998

Mechanistically, the study found that curcuminoids suppressed the expression of transcription factors specificity protein 1 (Sp1), Sp3, and Sp4, as well as several Sp-regulated oncogenic genes in SW480 cells