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The Phase 3 SYNERGY trial (NCT06859268) will evaluate whether retatrutide can resolve steatohepatitis (liver inflammation) and fibrosis, endpoints that would be required for regulatory approval specifically for liver disease treatment

Environmental distribution of the mec cassette The search of over 18,000 metagenomes identified similar gene cassettes in 41 metagenomes from peatland, the deep subsurface, and marine systems (Figure 5, Figure S2)

1 H-NMR (CDCl 3 , 400 MHz): 0.85 (3H, t = 7.2, H-10), 1.24 (10H, m, H-5-9), 1.60 (2H, m, H-3), 2.31 (2H, t, H-2)

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