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Como esses compostos no foram amplamente estudados em humanos, possveis impactos aps anos de uso ainda so incertos

In addition, the ZFPG + US treatment down-regulated the expression of the fatty acid synthase ( FASN ) gene, which could enhance the occurrence of ferroptosis by altering lipid metabolism and increasing lipid peroxidation (Figs

Munoz-Pinedo et al., 2006)

Potassium-competitive acid blockers have also been recently highlighted to limit the development of IBDs, such as colitis, which is often associated with the long-term use of PPIs