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*Correspondence: Yong-Yu Yang, [email protected] This article was submitted to Diabetes: Molecular Mechanisms, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

To decipher the impact of the ligands on the proteins active site, we focused on the region known to play a crucial role in substrate binding

At the time of patient enrollment, none of the subjects had received either local or systemic therapy for at least 5 months and only those with stable vitiligo and with body surface area involvement less than 10% were included

These proteases may complement the hosts digestive enzymes, aiding in the breakdown of dietary proteins into smaller peptides and amino acids (Afrilasari and Meryandini, 2016