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Eur J Pain 2002;6:2534.ArticlePubMed 22

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ALDH1A1 and ALDH1A3 detoxify and protect cells from these and their use has become a common detoxification strategy in cancer treatment ( FIGURE 1 2.2 ALDH1 regulates the RA signaling pathway The ALDH1 enzyme family plays a pivotal role in retinol metabolism, serving dual functions: (1) mediating the reversible conversion between retinol and retinaldehyde and (2) catalyzing the irreversible oxidation of retinaldehyde to retinoic acid (RA) in retinal and other tissues

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If you suspect you've experienced a side effect from either medication, report it through the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk or via the Yellow Card app)