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The pain is related to inflammation of the nerves and is often described as burning, throbbing, stabbing, or an electric-shock sensation. Acetaminophen (Tylenol) Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) or naproxen (Aleve) Capsaicin topical patch (Qutenza) Anticonvulsant drugs such as gabapentin (Neurontin, Gralise) and pregabalin (Lyrica) Tricyclic antidepressants such as amitriptyline and nortriptyline (Pamelor) Numbing medications such as lidocaine Opioids such as tramadol, oxycodone, or morphine An injection of corticosteroids and local anesthetic Oral corticosteroids [W]hile [pain medications] can be somewhat helpful, they often have drawbacks, especially in older adults or individuals with certain health conditions like diabetes, Tout says

Thorough screening prevents adverse events and protects your clinic from liability

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Therefore, catalase has an indirect relationship with the oxidative stress component in the pathogenesis of AD

Cons: Requires self-education and comfort with needles