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Glutathione peroxidase-catalase cooperativity is required for resistance to hydrogen peroxide by mature rat oligodendrocytes

Clinical trials, including those with ustekinumab (anti-IL-12/23p40) and risankizumab (anti-IL-23p19), demonstrated no significant improvement over placebo, with ASAS40 responses at 12 weeks nearly identical between treated and control groups[37, 38]