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This screening protocol is likely to result in EL-10 molecules with both antagonistic and agonistic activities

Estrogens can provide additional protective support by directly stimulating hepatocytes to increase STAT5 activation through both GH-dependent and GH-independent mechanisms [73]

This anti-inflammatory effect is mediated via TGF- induction and subsequent upregulation of Smad expression (Gao et al., 2020b)

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Sterne JA, Hernn MA, Reeves BC et al (2016) ROBINS-I: A tool for assessing risk of bias in non-randomised studies of interventions