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Decorin increases 302% at 1 nanomolar concentration, and this small proteoglycan regulates collagen synthesis and organization, essentially serving as an architect for proper structural protein arrangement

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These compounds come from different biological origins and modulate different molecular pathways, which is why researchers often use them in combination rather than as substitutes: BPC-157's distinguishing research angle is its gastric origin and mucosal-protection phenotype : it is the only compound in this cluster with published preclinical evidence in GI mucosa models, and the only one routinely studied under oral administration

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