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Taken together, these findings suggest that KDS12025 exerts potent anti-aging effects by preventing neuronal loss, reversing atrophic astrocytes, extending lifespan, and enhancing astrocytic Hb expression in aging mice, highlighting its potential as a breakthrough therapeutic for combating H 2 O 2 -driven oxidative stress during aging

In patients with bilirubin 40 U/L), n3 PUFA supplementation was associated with a significant reduction in all three enzymes, ALT, AST and GGT

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Molecular mechanisms of synaptic dysregulation in fragile X syndrome and autism spectrum disorders

Bcl-2 phosphorylation triggers autophagy switch and reduces mitochondrial damage in limb remote ischemic conditioned rats after ischemic stroke