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The Anshen Dingzhi prescription, from the Qing Dynastys Yi Xue Xin Wu (1732 CE), improves anxiety by activating the SIRT1-PGC-1 pathway, mitigating mitochondrial dysfunction [224]

pmid:20618069 8

Research has also investigated ipamorelin in combination with GHRH analogs such as CJC-1295, exploring potential synergistic effects on GH secretion patterns in preclinical settings