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The way it works makes sense: GLP-1 mostly changes the brainstem circuits that control feeling full, while amylin changes the area postrema and the nucleus tractus solitarius, which affects different neural paths

Genetic and Environmental Risk Factors Family history of substance use disorder confers shared genetic vulnerability in dopamine reward pathway architecture, with heritability estimates for stimulant use disorder consistent with other SUDs at 40 to 60%

Overall, the chapter presents Goldberg as a passionate advocate for integrating holistic and conventional medicine, emphasizing the need to address environmental toxins and promote public health education