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Brutscher, L

CCR6 is a (weak) co-receptor for HIV entry and is of significance in the context of HIV permissiveness 22

Efferth and Kaina, 2010)

The DESTINY-CRC01 trial exemplified this principle, achieving 45.3% objective response rate in HER2 IHC3 + /ISH + patients while observing no responses in HER2-low cohorts, highlighting the importance of stringent expression criteria