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These extracts can enhance the overall effectiveness of the treatment

Of note, colistin has been shown to exert tremendous side effects causing renal and neurological toxicity with higher cumulative doses, therefore limiting its effective in vivo application (131)

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It was also reported that microglia are capable of removing incorrectly deposited myelin directly from the axon, contributing to the refinement of myelin sheaths, as shown in zebrafish and mice during development (Hughes and Appel, 2020