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A growing amount of studies have demonstrated that ferroptosis participates in the progression of many different diseases such as cancer [15], Alzheimers disease [16], Parkinsons disease [17], traumatic brain injury [18], rheumatoid arthritis (RA) [19], ischemia-reperfusion injury [20] and intervertebral disc degeneration [21]

It is synthesised within cells in two sequential ATP-dependent steps, and maintained in its biologically active reduced form (GSH) through the activity of glutathione reductase using NADPH

Together, they create a more comprehensive healing response than either peptide can achieve on its own

Curcumin : Present in turmeric, it enhances glutathione enzyme activity ( Free Radical Biology and Medicine , 2016)

PMID: 33842899